Which antibiotic is a quinolone?

Get ready for the MDC Pharmacokinetics (PK) II Exam. Study with flashcards and multiple choice questions, each offering hints and explanations. Excel in your exam preparation!

Multiple Choice

Which antibiotic is a quinolone?

Explanation:
Quinolones kill bacteria by blocking enzymes essential for DNA replication, mainly DNA gyrase and topoisomerase IV. Ofloxacin is a fluoroquinolone, a member of this class, so it shares that mechanism and is considered a quinolone. The other drugs are from different classes: minocycline is a tetracycline that inhibits the 30S ribosome; amoxicillin is a beta-lactam that disrupts cell wall synthesis; rifampicin inhibits bacterial RNA polymerase. Thus, Ofloxacin is the quinolone among the options.

Quinolones kill bacteria by blocking enzymes essential for DNA replication, mainly DNA gyrase and topoisomerase IV. Ofloxacin is a fluoroquinolone, a member of this class, so it shares that mechanism and is considered a quinolone. The other drugs are from different classes: minocycline is a tetracycline that inhibits the 30S ribosome; amoxicillin is a beta-lactam that disrupts cell wall synthesis; rifampicin inhibits bacterial RNA polymerase. Thus, Ofloxacin is the quinolone among the options.

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