Which antibiotic is a fluoroquinolone included in the material?

• A. Rifampicin
• B. Ofloxacin
• C. Minocycline
• D. Amoxicillin

Answer: (B)

Fluoroquinolones target bacterial DNA replication by inhibiting DNA gyrase and topoisomerase IV, enzymes essential for maintaining and duplicating DNA. Ofloxacin is a member of this class, so it fits the description of a fluoroquinolone among the options. Rifampicin is a rifamycin that inhibits RNA synthesis by targeting RNA polymerase, not a fluoroquinolone. Minocycline is a tetracycline that blocks the 30S ribosomal subunit, disrupting protein synthesis. Amoxicillin is a beta-lactam antibiotic that inhibits cell wall synthesis. Therefore, Ofloxacin is the fluoroquinolone in the list.