Given Cl = 10 L/h and Vd = 40 L, calculate t1/2.

Get ready for the MDC Pharmacokinetics (PK) II Exam. Study with flashcards and multiple choice questions, each offering hints and explanations. Excel in your exam preparation!

Multiple Choice

Given Cl = 10 L/h and Vd = 40 L, calculate t1/2.

Explanation:
In first-order pharmacokinetics, half-life is given by t1/2 = 0.693 × Vd / Cl. With Vd = 40 L and Cl = 10 L/h, t1/2 = 0.693 × 40 / 10 = 27.72 / 10 = 2.772 hours, which is about 2.77 h. The other numbers would come from using a different constant, or from mixing up the order of the factors, but using the standard formula with the given values gives 2.77 hours.

In first-order pharmacokinetics, half-life is given by t1/2 = 0.693 × Vd / Cl. With Vd = 40 L and Cl = 10 L/h, t1/2 = 0.693 × 40 / 10 = 27.72 / 10 = 2.772 hours, which is about 2.77 h. The other numbers would come from using a different constant, or from mixing up the order of the factors, but using the standard formula with the given values gives 2.77 hours.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy